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Lab of Space & Special Environment for Skeletal System Health Science and Engineering

日期:2019年11月21日 16:37 作者: 关注:[]


  Research members

Prof. Peng Shang

Founding Dean of School of Life Sciences, Northwestern Polytechnical University (NPU); Director of the Key Laboratory for Space Biosciences & Biotechnology; Former dean of Research & Development Institute Shenzhen, NPU; Member of International Academy of Astronautics (IAA); Member of the International Astronautical Federation (IAF); Chair of Membership Committee, International Chinese Musculoskeletal Research Conference (ICMRC); Member of the Executive Board, Chinese Society of Space Research; Vice director of Committee of Space Life Science, Chinese Society of Space Research; Executive Director of Society for Cell biology in Shaanxi Province; Affiliate member of Center for Space Medicine, Baylor College of Medicine, USA.

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  Research interests

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  Recent publications

  1.     Wang SH, Shang P*.      Iron and magnetic: new research direction of the ferroptosis-based cancer      therapy. AM J CANCER RES, 2018, 8(10):1933-1946.

        2.    Dong      D, Shang P*. The role of iron metabolism in cancer therapy      focusing on tumor-associated macrophages. J Cell Physiol, 2018, 234(6):8028-2039.

        3.    Ting      HY, Shang P*.     Osteoclast-derived      exosomes inhibit osteogenic differentiation through Wnt/β-catenin  signaling pathway in simulated microgravity                 model. Acta Astronaut, 2018,      154:140-152.

4.    Yang J, Shang P*. Effects of Iron Overload and Oxidative Damage on the Musculoskeletal System in the Space Environment: Data from Spaceflights and Ground-Based Simulation Models. Int J Mol Sci, 2018,19(9): 2608.

        5.    Zhang      J, Shang P*. Effects of static magnetic fields on bone      microstructure and mechanical properties in mice. Electromagn Biol Med,      2018: 1-8.

        6.    Yang      P, Shang P*. Moderate tibia axial loading promotes discordant      response of bone composition parameters and mechanical properties in a  

                hindlim b unloading rat model. J Musculoskelet Neuronal Interact,      2018,18(2): 152-164.

7.     Shen Y, Shang P*. Transferrin receptor 1 in cancer: a new sight for cancer therapy. American Journal of Cancer Research. 2018, 8(6):916-931.

8.     Shen Y, Shang P*. Iron metabolism gene expression and prognostic features of hepatocellular carcinoma. Journal of Cellular Biochemistry. 2018, DOI:10.1002/jcb.27184.

9.     Yang J,Shang P*. Iron overload involved in the enhancement of unloading-induced bone loss by hypomagnetic field. Bone. 2018, 114:235-245.

10.   Lv H, Shang P*. The significance, trafficking and determination of labile iron in cytosol, mitochondria and lysosomes. Metallomics. 2018. DOI:10.1039/c8mt00048d.

11.   Zhou LF, Shang P*. Alternations in cellular iron metabolism provide more therapeutic opportunities for cancer. International Journal of Molecular Sciences. 2018, 19, 1545.

12.   Zhao B, Shang P*. Iron-dependent cell death as executioner of cancer stem cells. Journal of Experimental & Clinical Cancer Research. 2018, 37 (1):79.

13.   Liu ZL, Shang P*. CRISPR disruption of TCTP gene impaired normal development in the silkworm Bombyx mori. Insect Science. 2018.

14.   Zhang J, Shang P*. Effects of static magnetic fields on bone microstructure and mechanical properties in mice. Electromagnetic Biology and Medicine 2018, 1-8.

15.   Yang J, Shang P*. Regulation of Osteoblast Differentiation and Iron Content in MC3T3-E1 Cells by Static Magnetic Field with Different Intensities. Biol Trace Elem Res, 2018,184(1): 214-225.

16.   Yang PF, Shang P*. Deformation regimes of collagen fibrils in cortical bone revealed by in situ morphology and elastic modulus observations under mechanical loading. Journal of the Mechanical Behavior of Biomedical Materials. 2017, 79: 115-121.

         17.Liu      ZL, Shang P*.      MicroRNA-14 regulates larval development time in Bombyx mori. Insect      Biochemistry and Molecular Biology. 2018, 93: 57-65.

         18. Zhang      J, Shang P*. Nitric oxide modulates the      responses of osteoclast formation to static magnetic fields. Electromagnetic      Biology and Medicine. 201                 8, 37(1)23-24.

         19.  Zhang      J,      Shang P*. Differences in      responses to X-ray exposure between osteoclast and osteoblast cells. Journal      of Radiation Research. 2017, 5                 8(6): 791-802.

          20. Yang      J, Shang P*. Glucocorticoid: A potential role in      microgravity-induced bone loss. Acta Astronautica, 2017,140: 206-212.

          21. Zhang      J, Shang P*. Regulation of osteoclast differentiation by      static magnetic fields. Electromagnetic Biology and Medicine. 2017,      36(1):8-19.

          22. Xu      H, Shang P*. Impact of flow shear stress on morphology of      osteoblast-like IDG-SW3 cells. J Bone Miner Metab, 2017,36(5): 529-536.

          23. Xu      H, Shang P*. Blockage of hemichannels alters gene expression      in osteocytes in a high magneto-gravitational environment. Front Biosci      (Landma                  rk Ed), 2017,22: 783-794.

          24. Song      S, PengShang*. Total Flavonoids of Drynariae Rhizoma Prevent      Bone Loss Induced by Hindlimb Unloading in Rats. Molecules, 2017,22(7).

 

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